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Beilstein J. Org. Chem. 2018, 14, 2348–2353, doi:10.3762/bjoc.14.210
Graphical Abstract
Figure 1: Scope of the water-mediated synthesis of 4-acyl-NH-1,2,3-triazoles. General conditions: enaminone 1...
Scheme 1: The gram scale synthesis of 3a: (a) before reaction; (b) completed reaction; (c) the purified produ...
Scheme 2: The proposed reaction mechanism.